A master’s thesis entitled (The importance of biomarkers such as lipocalin bound to neutrophil gelatin and type I kidney injury molecule in diagnosing chronic kidney failure) was discussed in the Clinical Biochemistry branch, by student Karar Yasser Hassan and under the supervision of Assistant Professor Dr. Haider Abd Jabbar Al-Ammar.
The thesis aimed to evaluate and compare NGAL and KIM-1 levels in blood and kidney function tests in patients with chronic kidney disease, establish the association between them and draw attention to the potential screening value of these biomarkers.
The letter concluded that there is an increase in the level of biomarkers such as neutrophil gelatinase-related lipocalin and kidney injury molecule type 1 in the serum of patients suffering from chronic renal failure compared to a group of healthy people, which may be a good indicator for the diagnosis of chronic renal failure.
The letter recommended the use of other markers, such as asymmetric dimethylarginine and symmetric dimethylarginine, for their efficiency in monitoring and diagnosing chronic renal dysfunction. There is a need for other techniques, such as PCR, in diagnosing the disease.